| Active substance |
Metformin Hydrochloride |
| Also known as |
Metformin HCL |
| Blood pressure |
Can lead to a slight reduction in blood pressure |
| Chemical name |
Metformin hydrochloride |
| Dosage (medical) |
Typically starting at 500 mg twice a day or 850 mg once a day, up to a maximum of 2000-2550 mg per day depending on the patient's response and tolerance |
| Dosage (sports) |
Not typically prescribed for sports enhancement |
| Effects |
Reduces hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization |
| FORM |
100 pills x 1000 mg |
| Formula |
C4H11N5В·HCl |
| Half-life |
Approximately 6.2 hours |
| Hepatotoxicity |
Low risk |
| Lab Test |
Monitoring of renal function and serum electrolytes recommended |
| Main action |
Antihyperglycemic agent |
| Side effects |
Gastrointestinal disturbances (such as diarrhea, nausea, vomiting), vitamin B12 deficiency, lactic acidosis (rare but serious) |
| Storage conditions |
Store at room temperature, away from moisture and light |
| Substance class |
Biguanide |
| Trade name |
Glucophage, Glumetza, others |
| Use in sports |
Not commonly used as a performance enhancer, but some athletes might use it for weight management |
| Water Retention |
Does not cause significant water retention |
| Manufacturer |
MERCK |
